On Thursday, Sept. 9, 2021, President Joe Biden signed executive orders requiring federal workers and contractors to get vaccinated against COVID-19. Biden also directed the Occupational Safety and Health Administration (OSHA) to draft a new emergency rule requiring all businesses with 100 or more employees to ensure all of their workers are either tested for COVID-19 once a week or fully vaccinated.

The New York Health and Essentials Rights Act (NY HERO Act) amends labor laws covering all private employers to prevent occupational exposure to airborne infectious disease.

On May 28, 2021, the Equal Employment Opportunity Commission (EEOC) added new frequently asked questions (FAQs) on employer COVID-19 vaccination programs and the restrictions imposed on them by the Americans with Disabilities Act (ADA) and other federal fair employment laws.

On May 21, 2021, OSHA changed its frequently asked question concerning vaccination reporting to not require employers to report employees' adverse reactions to the COVID-19 vaccination.

The New York Hero Act requires businesses to implement safety measures to prevent the further spread of COVID-19.